Guillain Barre in ED - acute inflammatory demyelinating polyneuropathy - ascending motor paresis with lower motor neurone features with some dyautonomia and cranial nerve abn - don’t forget to check FVC and FIP.

GBS presents occasionally to ED as paediatric or adult weakness. Key components of the clinical picture include

-varying degrees of lower limb weakness ( sometimes presenting as new onset ‘cannot walk’), LMN signs in ascending pattern
-usually mostly motor, but some sensory deficit
-decreased or equivocal reflexes
- dysautonomia (fluctuations in hr bp diaphoresis )
- respiratory failure with chest wall muscle weakness

Remember to check FVC (<15L/kg) and FIP (<-25 cmh2o) as indicators for intubation and mechanical ventilation.
Avoid suxamethonium and optimize vitals with short acting vasoactive agents ( esmolol if hypertensive, noradrenaline if hypotensive) prior to RSI.